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Direct Plotting of Three-Dimensional Hollow Fiber Scaffolds Based on Concentrated Alginate Pastes for Tissue Engineering

Authors

  • Yongxiang Luo,

    1. Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus and Medical Faculty of Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany
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  • Anja Lode,

    1. Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus and Medical Faculty of Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany
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  • Michael Gelinsky

    Corresponding author
    1. Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus and Medical Faculty of Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany
    2. DFG Research Center and Cluster of Excellence for Regenerative Therapies Dresden (CRTD)
    • Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus and Medical Faculty of Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany.
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  • Dedicated to Professor Wolfgang Pompe on the occasion of his 70th birthday

Abstract

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Porous scaffolds for tissue engineering applications consisting of hollow alginate fibers are presented. They are prepared using self-made shell/core nozzles and a 3D plotting device. Such materials open up the possibility to generate biodegradable tissue constructs with a preformed vascular system or can act as matrices for engineering of complex organs or 3D tissue models.

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