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A Diamond Nanoneedle Array for Potential High-Throughput Intracellular Delivery

Authors

  • Xianfeng Chen,

    Corresponding author
    1. Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China
    • Xianfeng Chen, Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China

      Guangyu Zhu, Department of Chemistry and Biology, City University of Hong Kong, Hong Kong SAR, P. R. China.

      Wenjun Zhang, Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China

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  • Guangyu Zhu,

    Corresponding author
    1. Department of Chemistry and Biology, City University of Hong Kong, Hong Kong SAR, P. R. China
    • Xianfeng Chen, Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China

      Guangyu Zhu, Department of Chemistry and Biology, City University of Hong Kong, Hong Kong SAR, P. R. China.

      Wenjun Zhang, Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China

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  • Yang Yang,

    1. Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China
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  • Beilei Wang,

    1. Department of Chemistry and Biology, City University of Hong Kong, Hong Kong SAR, P. R. China
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  • Li Yan,

    1. Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China
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  • Kenneth Yin Zhang,

    1. Department of Chemistry and Biology, City University of Hong Kong, Hong Kong SAR, P. R. China
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  • Kenneth Kam-Wing Lo,

    1. Department of Chemistry and Biology, City University of Hong Kong, Hong Kong SAR, P. R. China
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  • Wenjun Zhang

    Corresponding author
    1. Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China
    • Xianfeng Chen, Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China

      Guangyu Zhu, Department of Chemistry and Biology, City University of Hong Kong, Hong Kong SAR, P. R. China.

      Wenjun Zhang, Center of Super-Diamond and Advanced Films (COSDAF) and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, P. R. China

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Abstract

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A dense diamond nanoneedle array is capable of rapidly and conveniently delivering fluorescent probe and drug molecules to a large number of cells. This simple approach paves the way for potential high-throughput delivery of genes, drugs, and fluorescent probes into cells without endocytosis.

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