SEARCH

SEARCH BY CITATION

Keywords:

  • co-delivery;
  • antigens;
  • CpG ODN;
  • immune;
  • dual-mode imaging
Thumbnail image of graphical abstract

Europium-doped GdPO4 hollow spheres/polymer core-shell nanoparticles are functionalized with ovalbumin (OVA) as a model antigen and an oligonucleotide (CpG) that stimulates the immune response. These functionalized core-shell nanoparticles are used as vaccines, where they enable efficient delivery of an antigen to target sites, tracking of the vaccines using non-invasive clinical imaging technology.