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Keywords:

  • bacteria;
  • cell adhesion;
  • fibronectin;
  • integrin;
  • interface
Thumbnail image of graphical abstract

Lactococcus lactis is modified to express a fibronectin fragment (FNIII7-10) as a membrane protein. This interphase, based on a living system, can be further exploited to provide spatio-temporal factors to direct cell function at the material interface. This approach establishes a new paradigm in biomaterial surface functionalization for biomedical applications.