Cancer Therapy: Cooperative, Nanoparticle-Enabled Thermal Therapy of Breast Cancer (Adv. Healthcare Mater. 1/2012)



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An efficient thermal ablation agent was developed by confining gold nanoshells into nanopores of silicon microparticles. On page 84, Mauro Ferrari and co-workers show how near-infrared laser light triggers enhanced heat generation of gold nanoshells, by exploiting nanoscale cooperative effects inside microparticles. A multifold increase in thermal therapy efficacy was achieved for breast cancer in cell culture and in animal tumor models.