Drug Delivery: Functional Silica Nanoparticles for Redox-Triggered Drug/ssDNA Co-delivery (Adv. Healthcare Mater. 6/2012)

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Abstract

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A mesoporous silica nanoparticle based co-delivery system for redox-triggered simultaneous release of drug and single strand DNA is reported by Y. L. Zhao and co-workers on page 690. High co-delivery efficiency of the biocompatible nanoparticles has been demonstrated in vitro, exhibiting the successful release of both anticancer drug doxorubicin and single strand DNA into Hela cancer cells for improved apoptosis.

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