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Drug Delivery: Functional Silica Nanoparticles for Redox-Triggered Drug/ssDNA Co-delivery (Adv. Healthcare Mater. 6/2012)

  1. Xing Ma1,
  2. Kim Truc Nguyen2,
  3. Parijat Borah2,
  4. Chung Yen Ang2,
  5. Yanli Zhao1,2,*

Article first published online: 2 NOV 2012

DOI: 10.1002/adhm.201290027

Issue

Advanced Healthcare Materials

Advanced Healthcare Materials

Volume 1, Issue 6, page 689, November, 2012

Additional Information

How to Cite

Ma, X., Nguyen, K. T., Borah, P., Ang, C. Y. and Zhao, Y. (2012), Drug Delivery: Functional Silica Nanoparticles for Redox-Triggered Drug/ssDNA Co-delivery (Adv. Healthcare Mater. 6/2012). Advanced Healthcare Materials, 1: 689. doi: 10.1002/adhm.201290027

Author Information

  1. 1

    Materials Science and Engineering School, Nanyang Technological University, 50 Nanyang Avenue, 639798 Singapore, Web: www.ntu.edu.sg/home/zhaoyanli

  2. 2

    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371 Singapore

*Materials Science and Engineering School, Nanyang Technological University, 50 Nanyang Avenue, 639798 Singapore, Web: www.ntu.edu.sg/home/zhaoyanli.

Publication History

  1. Issue published online: 2 NOV 2012
  2. Article first published online: 2 NOV 2012

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Keywords:

  • controlled release;
  • drug delivery;
  • gene therapy;
  • mesoporous silica nanoparticles;
  • redox
Thumbnail image of graphical abstract

A mesoporous silica nanoparticle based co-delivery system for redox-triggered simultaneous release of drug and single strand DNA is reported by Y. L. Zhao and co-workers on page 690. High co-delivery efficiency of the biocompatible nanoparticles has been demonstrated in vitro, exhibiting the successful release of both anticancer drug doxorubicin and single strand DNA into Hela cancer cells for improved apoptosis.

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