Doxorubicin Release: Hybrid Organic Nanotubes with Dual Functionalities Localized on Cylindrical Nanochannels Control the Release of Doxorubicin (Adv. Healthcare Mater. 6/2012)

Authors

  • Wuxiao Ding,

    1. Nanotube Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), Tsukuba Central 5, Higashi 1-1-1, Tsukuba 305-8565, Ibaraki, Japan
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  • Naohiro Kameta,

    1. Nanotube Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), Tsukuba Central 5, Higashi 1-1-1, Tsukuba 305-8565, Ibaraki, Japan
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  • Hiroyuki Minamikawa,

    1. Nanotube Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), Tsukuba Central 5, Higashi 1-1-1, Tsukuba 305-8565, Ibaraki, Japan
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  • Momoyo Wada,

    1. Nanotube Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), Tsukuba Central 5, Higashi 1-1-1, Tsukuba 305-8565, Ibaraki, Japan
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  • Toshimi Shimizu,

    1. Nanotube Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), Tsukuba Central 5, Higashi 1-1-1, Tsukuba 305-8565, Ibaraki, Japan
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  • Mitsutoshi Masuda

    Corresponding author
    1. Nanotube Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), Tsukuba Central 5, Higashi 1-1-1, Tsukuba 305-8565, Ibaraki, Japan
    • Nanotube Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), Tsukuba Central 5, Higashi 1-1-1, Tsukuba 305-8565, Ibaraki, Japan.
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Abstract

original image

Novel cylindrical nanocapsules, with tunable inner surface, enable controlled release of the encapsulated anticancer drug doxorubicin. On page 699, M. Masuda and co-workers develop such nanocapsules with dual functionalities (–COOH and benzyloxycarbonyl) localized on their cylindrical nanochannels via a co-assembly of two rationally designed glycolipids.

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