Cytokine Removal: Hierarchical Porous Carbide-Derived Carbons for the Removal of Cytokines from Blood Plasma (Adv. Healthcare Mater. 6/2012)

Authors

  • Volker Presser,

    1. Department of Materials Science and Engineering, A. J. Drexel Nanotechnology Institute, Drexel University, 3141 Chestnut Street, Philadelphia, PA, 19104, USA
    2. Energy Materials Group, INM - Leibniz-Institut für Neue Materialien gGmbH, Campus D2 2, D-66123 Saarbrücken, Germany
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  • Sun-Hwa Yeon,

    1. Distributed Power Generation and Energy Storage Group, Korea Institute of Energy Research, Daejeon, 305-343, South Korea
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  • Cekdar Vakifahmetoglu,

    1. Department of Mechanical Engineering, Istanbul Kemerburgaz University, Mahmutbey Dilmenler Caddesi, No:26, 34217 Bagcilar, Istanbul, Turkey
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  • Carol A. Howell,

    1. School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton BN2 4GJ, UK
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  • Susan R. Sandeman,

    1. School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton BN2 4GJ, UK
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  • Paolo Colombo,

    1. Dipartimento di Ingegneria Meccanica–Settore Materiali, University of Padova, 35131 Padova, Italy & Department of Materials Science and Engineering, The Pennsylvania State University, University Park, PA 16802, USA
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  • Sergey Mikhalovsky,

    Corresponding author
    1. School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton BN2 4GJ, UK
    2. School of Engineering, Nazarbayev University, 53 Kabanbay batyr ave., Astana, 010000, Kazakhstan
    • School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton BN2 4GJ, UK.
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  • Yury Gogotsi

    Corresponding author
    1. Department of Materials Science and Engineering, A. J. Drexel Nanotechnology Institute, Drexel University, 3141 Chestnut Street, Philadelphia, PA, 19104, USA
    • Department of Materials Science and Engineering, A. J. Drexel Nanotechnology Institute, Drexel University, 3141 Chestnut Street, Philadelphia, PA, 19104, USA
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Abstract

original image

Carbide-derived carbons with hierarchical porosity derived from a polymer precursor can be used for the extracorporeal removal of pro- and anti-inflammatory cytokines. The removal rates scale with the surface area of pores large enough to accommodate the protein molecules and this method has potential for efficacious treatment of sepsis, one of the major challenges in healthcare. Further information can be found in the Communication by S. Mikhalovsky, Y. Gogotsi, and co-workers on page 796.

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