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Micropatterning Hydrophobic Liquid on a Porous Polymer Surface for Long-Term Selective Cell-Repellency

Authors

  • Erica Ueda,

    1. Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Postfach 3640, 76021 Karlsruhe, Germany
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  • Pavel A. Levkin

    Corresponding author
    1. Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Postfach 3640, 76021 Karlsruhe, Germany
    2. Department of Applied Physical Chemistry, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany
    • Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Postfach 3640, 76021 Karlsruhe, Germany.

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Abstract

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A simple method to form precise micropatterns of hydrophobic liquids using porous hydrophilic–hydrophobic substrates is presented. The micropatterns of hydrophobic liquid exhibit long-term stability, excellent cell-repellency, no cytotoxicity, and are more efficient than conventional PEG or superhydrophobic surfaces in controlling eukaryotic cell adhesion.

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