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Microneedle Electrodes Toward an Amperometric Glucose-Sensing Smart Patch

Authors

  • Michael A. Invernale,

    1. The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
    2. Department of Anesthesiology, Children's Hospital Boston, Boston, MA, USA
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  • Benjamin C. Tang,

    1. The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
    2. Department of Anesthesiology, Children's Hospital Boston, Boston, MA, USA
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  • Royce L. York,

    1. The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
    2. Department of Anesthesiology, Children's Hospital Boston, Boston, MA, USA
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  • Long Le,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
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  • David Yupeng Hou,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
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  • Daniel G. Anderson

    Corresponding author
    1. The David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
    2. Department of Anesthesiology, Children's Hospital Boston, Boston, MA, USA
    3. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
    4. Harvard-MIT Division of Health Science Technology, Massachusetts Institute of Technology 45 Carleton Street, Cambridge, MA, USA
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Abstract

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Here, efforts toward the development of a microneedle-based glucose sensor or “smart patch” for intradermal glucose sensing are described. Metallic microneedle array electrodes, conducting polymers, and glucose oxidase form the sensor platform. This work represents the first steps toward the development of painless, transdermal-sensing devices for continuous glucose monitoring

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