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Keywords:

  • capsules;
  • hydrophobic drug delivery;
  • polysaccharide;
  • biocompatibility;
  • sonochemistry
Thumbnail image of graphical abstract

Cells like sugar. General synthesis and potential of intracellular hydrophobic drug delivery of single-component polysaccharide capsules are pursued. The capsules can be generally assembled through hydrogen bonding networks but show striking shell robustness. The evidenced cell internalization, stimuli-responsiveness to local pH changes and high biocompatibilities of the capsules specifically favor their potential intracellular drug delivery