Stem Cells: Surface Bound Amine Functional Group Density Influences Embryonic Stem Cell Maintenance (Adv. Healthcare Mater. 4/2013)



original image

The back cover image shows an octadiene–allylamine plasma polymer gradient surface with colonies of embryonic stem cells attached, as described by Nicolas H. Voelcker and co-workers on page 585. Stem cell colonies spread out on regions of the surface with higher amine group density, differentiating into more mature cell types. In contrast, smaller rounded colonies, consisting of proliferating stem cells, form high methyl group density areas.