Electrical Stimulation of Myoblast Proliferation and Differentiation on Aligned Nanostructured Conductive Polymer Platforms (pages 801–808)
Anita F. Quigley, Joselito M. Razal, Magdalena Kita, Rohoullah Jalili, Amy Gelmi, Anthony Penington, Raquel Ovalle-Robles, Ray H. Baughman, Graeme M. Clark, Gordon G. Wallace and Robert M. I. Kapsa
Version of Record online: 14 SEP 2012 | DOI: 10.1002/adhm.201200102
In this study, nanostructured conductive platforms synthesized from aligned multiwalled carbon nanotubes and polypyrrole are investigated as myo-regenerative scaffolds. Myotube formation follows a linear path on the platforms coinciding with extent of nanotopography. In addition, electrical stimulation enhances myo-nuclear number and differentiation. These studies demonstrate that conductive polymer platforms can be used to influence muscle cell behaviour through nanostructure and electrical stimulation.