Fluorescent sensors and color-change indicators for molecules

Authors

  • Akihiko Ueno

    Corresponding author
    1. Department of Bioengineering, Faculty of Bioscience and Biotechnology Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama 227 (Japan)
    • Department of Bioengineering, Faculty of Bioscience and Biotechnology Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama 227 (Japan)
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Abstract

Cyclodextrins substituted with a fluorescent group can be employed as molecular sensors. The Figure shows how the fluorophore usually occupies the hydrophobic interior of the cyclodextrin host. On addition of a guest, the fluorophore is displaced from the cavity, resulting in a change in its spectral response. Recent progress with this and related molecular sensors is discussed.

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