Polymeric drug delivery systems


  • The authors wish to thank the CICYT for financial support proviaded through grants Mat-92-0198, Mat-93-0749-C03-01, and FIS-94/0033, which have enabled much of this work to be performed. They are also grateful to Prof. Jose Luis Serrano for the invitation to contribute to this issue.


Controlled drug release- and targeted drug delivery systems based on polymers are reviewed. The design of polymer-drug systems, for example the one shown in the Figure, which contains a solubilizer, the drug linked to the backbone through a spacer, and a targeting moiety for guiding the drug to the desired site, and the factors which influence their effectiveness are discussed.

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