Polymeric drug delivery systems

Authors


  • The authors wish to thank the CICYT for financial support proviaded through grants Mat-92-0198, Mat-93-0749-C03-01, and FIS-94/0033, which have enabled much of this work to be performed. They are also grateful to Prof. Jose Luis Serrano for the invitation to contribute to this issue.

Abstract

Controlled drug release- and targeted drug delivery systems based on polymers are reviewed. The design of polymer-drug systems, for example the one shown in the Figure, which contains a solubilizer, the drug linked to the backbone through a spacer, and a targeting moiety for guiding the drug to the desired site, and the factors which influence their effectiveness are discussed.

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