Advanced Materials

The crystallization of polar, channel-type inclusion compounds: Property-directed superamolecular synthesis


  • This work has been supported by NFP 36 (4036-043932). NF (20-4316.95) and by the Hochschulstiftung (University of Berne. no. 35/96). We thank Dr. G. Raabe (RWTH Aachen) and Dr. M. Schmidt (Hoechst) for preliminary calculations of electrostatic guest-guest interactions. We thank Prof. H.-B. Bürg for drawing our attention to Markow's formalism and Dr. P. J. Langley for editing the manuscript.


How can the efficiency of formation of polar materials be improved? The work presented ehre makes use of the concept of supramolecular synthons, resulting in an inclusion formation approach that produces a nearly four times higher yield of polar crystal structures than the crystallization of dipolar molecules alone. The xample of co-crystallization of racemic all-trans perhydrotriphenylene (PHTP) with linear acceptors or donors is analyzed, and it is suggested that thie “Property-directed” synthesis has a potentially high degree of predictability.