Advanced Materials

Micropatterning fluid membranes


  • Supported in part by the Joint Services Electronics Program (G. S. Kino), NSF Biophysics Program, NSF (H. M. McConnell), and an NSF-sponsored User Grant at the Stanford Nanofabrication Facility. We thank H. M. McConnell, G. S. Kino and D. M. Bloom for advice and encouragement.


An application of photolithographic patterning is described for producing a self-assembled membrane that is fluid over some areas and immobilized or absent in others, as directed by the patterning on the support (see Figure). This is an important step towards forming a specific interface between living cells and silicon electronics. (Figure reprinted from Science1997 275, 651–653; ©1997 AAAS)

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