The authors gratefully acknowledge funding for their research in this area from the National Institute of Dental and Craniofacial Research (NIH).
Peptide and Protein Presenting Materials for Tissue Engineering†
Article first published online: 16 JAN 2004
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 16, Issue 1, pages 17–25, January, 2004
How to Cite
Hirano, Y. and Mooney, D. J. (2004), Peptide and Protein Presenting Materials for Tissue Engineering. Adv. Mater., 16: 17–25. doi: 10.1002/adma.200300383
- Issue published online: 16 JAN 2004
- Article first published online: 16 JAN 2004
- Manuscript Accepted: 8 AUG 2003
- Manuscript Received: 12 MAR 2003
- Tissue Engineering
Tissue engineering aims to create new tissues and organs to replace those lost to disease, trauma, or congenital defects. However, considerable instruction must be given to the cells forming these new tissues if one is to create a tissue structurally and functionally similar to the native tissue. Materials are ideal for the local presentation of various peptides and proteins that can bind to cell surface receptors and regulate cell function. An overview of techniques to present peptides and proteins from materials, and the utility of these systems in engineering tissues in vitro and in vivo is presented.