Generation of Uniform Colloidal Assemblies in Soft Microfluidic Devices

Authors

  • G.-R. Yi,

    1. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea
    2. Present address: Department of Chemical Engineering, University of California, Santa Barbara, CA 93106, USA.
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  • T. Thorsen,

    1. Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125(USA)
    2. Present address: Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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  • V.N. Manoharan,

    1. Department of Chemical Engineering, University of California, Santa Barbara, CA 93106, USA
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  • M.-J. Hwang,

    1. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea
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  • S.-J. Jeon,

    1. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea
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  • D.J. Pine,

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  • S.R. Quake,

    1. Department of Applied Physics, California Institute of Technology, Pasadena, CA 91125(USA)
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  • S.-M. Yang

    1. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Korea
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  • This work was supported by the US NSF grant number CTS-0221809, the Brain Korea 21 Program, and the Korean National Nanotechnology Project. We also thank Prof. J H. Hahn for helpful discussions on sorting experiments.

Abstract

A microfluidic device is used to generate uniform emulsion droplets containing monodisperse latex spheres at specific intervals by shearing off the tip of the incoming aqueous phase at the junction of two microfluidic channels (see Figure). The water-in-oil emulsions are converted to uniform colloidal assemblies of latex spheres by slowly removing water from the aqueous emulsion droplets.

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