We thank Professor Robert Sauer for the use of the Aviv spectropolarimeter and Jill Sakata for help with the bacterial expression of the peptides. We acknowledge the support of the National Institutes of Health (Grant #DE-13023).
Coiled-Coil Peptide-Based Assembly of Gold Nanoparticles†
Article first published online: 20 APR 2004
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 16, Issue 11, pages 915–918, June, 2004
How to Cite
Stevens, M. M., Flynn, N. T., Wang, C., Tirrell, D. A. and Langer, R. (2004), Coiled-Coil Peptide-Based Assembly of Gold Nanoparticles. Adv. Mater., 16: 915–918. doi: 10.1002/adma.200306430
- Issue published online: 17 JUN 2004
- Article first published online: 20 APR 2004
- Manuscript Accepted: 23 JAN 2004
- Manuscript Received: 6 NOV 2003
The coiled-coil-based assembly of gold nanoparticles (see Figure and cover) is demonstrated. Control over the assembly and disassembly of nanostructures is achieved under mild conditions (near-neutral pH and ambient temperature). The flexibility in design afforded by varying the peptide sequence to produce coiled coils with different stabilities is also highlighted by the generation of more stable binary nanoparticle systems with controlled spacing and architecture.