Inorganic–Biomolecular Hybrid Nanomaterials as a Genetic Molecular Code System


  • This study was supported by the Korean Ministry of Science and Technology through the National Research Laboratory Program (1999) and National R&D Project for Nano Science and Technology, and in part by the Brain Korea 21 program. Supporting Information is available online from Wiley Interscience or from the author.


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A molecular-level coding method utilizing DNA base pairs as code units has been systemized. The system consists of four steps: encoding, encrypting, decrypting and decoding (see Figure), which are realized by tailor-made nanohybrids (DNA–layered double hydroxide (LDH) and polypyrrole–maghemite). The nanohybrids give solutions to the inherent problems which hamper DNA molecular code systems; stability in encrypting and rapidity in analysis.