Communication

Bicontinuous, Thermoresponsive, L3-Phase Silica Nanocomposites and Their Smart Drug-Delivery Applications

  1. J. H. Chang,
  2. C. H. Shim1,
  3. B. J. Kim1,
  4. Y. Shin2,
  5. G. J. Exarhos2,
  6. K. J. Kim1

Article first published online: 3 MAR 2005

DOI: 10.1002/adma.200400545

Issue

Advanced Materials

Advanced Materials

Volume 17, Issue 5, pages 634–637, March, 2005

Additional Information

How to Cite

Chang, J. H., Shim, C. H., Kim, B. J., Shin, Y., Exarhos, G. J. and Kim, K. J. (2005), Bicontinuous, Thermoresponsive, L3-Phase Silica Nanocomposites and Their Smart Drug-Delivery Applications. Adv. Mater., 17: 634–637. doi: 10.1002/adma.200400545

Author Information

  1. 1

    Korea Institute of Ceramic Engineering and Technology, Seoul 153-801, Korea

  2. 2

    Pacific Northwest National Laboratory, Richland, WA 99354, USA

Publication History

  1. Issue published online: 3 MAR 2005
  2. Article first published online: 3 MAR 2005
  3. Manuscript Accepted: 18 OCT 2004
  4. Manuscript Received: 13 APR 2004

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (395K)

Keywords:

  • Drug delivery;
  • Nanoporous materials;
  • Polymers, stimuli-responsive
Thumbnail image of graphical abstract

Bicontinuous, thermosensitive, L3-phase silica nanocomposites are prepared by self-assembly of silicified L3-phase silicates and L3-phase silicates integrated with thermoresponsive poly(N-isopropylacryl amide) (PNIPAm; see Figure). In the L3-PNIPAm material, interpenetrating nanoscale networks of silica and polymer gel are formed, with which highly controlled drug delivery is successfully demonstrated.

Get PDF (395K)