Advanced Materials

Three-Dimensional Bioactive and Biodegradable Scaffolds Fabricated by Surface-Selective Laser Sintering


  • The authors are grateful to Dr. Daniel Bratton for his technical advice. The authors also acknowledge the financial support of the Engineering and Physical Sciences Research Council (EPSRC) and the Wellcome Trust (Collaborative Research Initiative Grants No. 062760 and No. 073913). S. M. H is a Royal Society–Wolfson Research Merit Award Holder.


Surface-selective laser sintering (SSLS) has been developed for fabrication of three-dimensional polymer composite scaffolds with precise dimensions and intricate structure (see Figure), which are bioactive and biodegradable. SSLS allows sintering of polymer powders by melting only the surface layers of particles, which prevents overheating of internal domains, allowing incorporation of bioactive molecules into the structures.

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