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Keywords:

  • Cells;
  • Microfluidics;
  • Photopolymerization
Thumbnail image of graphical abstract

Integration of a microfluidic gradient generator and photopolymerization to fabricate novel hydrogels with tunable mechanical properties on the microscale (see Figure) is reported. This concept introduces a new class of materials that can be used to investigate the role of substrate elastic moduli in controlling cell morphology and cytoskeletal organization, and more generally, cell behavior.