This work was financially supported by CREST from the Japan Science and Technology Agency and was partly supported by Sekisui Chemical Co. Ltd. Supporting Information is available online from Wiley InterScience or from the author.
Freeze-Drying of Soft Nanoparticles with Projection Coronas Forms Three-Dimensional Microconstructs†
Article first published online: 1 JUL 2005
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 17, Issue 13, pages 1638–1643, July, 2005
How to Cite
Kaneko, T., Hamada, K., Chen, M. Q. and Akashi, M. (2005), Freeze-Drying of Soft Nanoparticles with Projection Coronas Forms Three-Dimensional Microconstructs. Adv. Mater., 17: 1638–1643. doi: 10.1002/adma.200401288
- Issue published online: 1 JUL 2005
- Article first published online: 1 JUL 2005
- Manuscript Accepted: 24 MAR 2005
- Manuscript Received: 6 AUG 2004
- Nanoparticles, assembly;
- Nanoparticles, polymer;
- Poly(ethylene glycol);
- Template-free assembly/synthesis
Freeze-drying of polymeric nanoparticles with projection coronas results in the successful formation of three-dimensional microconstructs with various morphologies, including hollow microspheres (see Figure), without a solid or colloidal template. The microconstructs have sufficient mechanical strength to redisperse successfully in water without collapsing, while they break into nanoparticles following successive freeze–thawing cycles.