Peptide Nanotubes: Simple Separation Using Size-Exclusion Columns and Use as Templates for Fabricating One-Dimensional Single Chains of Au Nanoparticles


  • This work was supported by the US Department of Energy (DE-FG-02-01ER45935). X.G. thanks Dr. Tsiola Areti at the Core Facilities for Imaging, Cell, and Molecular Biology in the Biology Department at Queens College—CUNY for the use of the transmission electron microscope.


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Straight single chains of Au nanoparticles have been synthesized using 10 nm diameter peptide nanotubes as templates (see Figure). The 6 nm Au nanoparticles grow in the gaps between the synthetic peptide coating the nanotubes which regulates the size, dispersity, interparticle distance, and crystallinity of the nanoparticles. The use of longer nanotubes results in longer chains.