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Keywords:

  • Biomaterials;
  • Cells;
  • Hydrogels;
  • Peptides;
  • Supramolecular materials;
  • Tissue engineering
Thumbnail image of graphical abstract

A number of short peptide amphiphiles consisting of dipeptides linked to fluorenylmethoxycarbonyl spontaneously form fibrous hydrogels under physiological conditions (see figure). The structural and physical properties of these gels are dictated by the amino acid sequence of the peptide building blocks, and the gels support the three-dimensional cell culture of chondrocytes.