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Protein/DNA/Inorganic Materials: DNA Binding to Layered α-Zirconium Phosphate Enhances Bound Protein Structure and Activity†
Article first published online: 24 MAR 2006
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 18, Issue 7, pages 939–942, April, 2006
How to Cite
Bhambhani, A. and Kumar, C. V. (2006), Protein/DNA/Inorganic Materials: DNA Binding to Layered α-Zirconium Phosphate Enhances Bound Protein Structure and Activity. Adv. Mater., 18: 939–942. doi: 10.1002/adma.200502230
- Issue published online: 24 MAR 2006
- Article first published online: 24 MAR 2006
- Manuscript Accepted: 23 NOV 2005
- Manuscript Received: 17 OCT 2005
Successful intercalation of calf thymus DNA into the galleries of layered alpha zirconium phosphate (α-Zr(HPO4)2· H2O, α-ZrP) was facilitated by met-hemoglobin (Hb) and tetrabutylammonium (TBA) hydroxide. Intercalation of DNA, in turn, improved the properties of the co-intercalated protein. The protein structure, for example, was improved significantly and activities were enhanced by more than fivefold.