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Communication

Rapid-Setting, Mesoporous, Bioactive Glass Cements that Induce Accelerated In Vitro Apatite Formation†

  1. Q. H. Shi1,
  2. J. F. Wang2,
  3. J. P. Zhang3,
  4. J. Fan1,
  5. G. D. Stucky1

Article first published online: 7 APR 2006

DOI: 10.1002/adma.200502292

Issue

Advanced Materials

Advanced Materials

Volume 18, Issue 8, pages 1038–1042, April, 2006

Additional Information

How to Cite

Shi, Q. H., Wang, J. F., Zhang, J. P., Fan, J. and Stucky, G. D. (2006), Rapid-Setting, Mesoporous, Bioactive Glass Cements that Induce Accelerated In Vitro Apatite Formation. Adv. Mater., 18: 1038–1042. doi: 10.1002/adma.200502292

Author Information

  1. 1

    Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA

  2. 2

    Department of Physics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, P.R. China

  3. 3

    Materials Department, University of California, Santa Barbara, CA 93106, USA

  1. †

    This work was supported by the MRSEC Program of the National Science Foundation under Award No. DMR05-20415 and by the Office of Naval Research under Grant No. N00014-04-1-0654. Supporting Information is available online from Wiley InterScience or from the author.

Publication History

  1. Issue published online: 7 APR 2006
  2. Article first published online: 7 APR 2006
  3. Manuscript Accepted: 17 DEC 2005
  4. Manuscript Received: 26 OCT 2005

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Keywords:

  • Bioactivity;
  • Biomedical materials;
  • Glass cements;
  • Mechanical properties;
  • Mesoporous materials;
  • Tissue engineering
Thumbnail image of graphical abstract

A rapid-setting, mesoporous, bioactive glass cement (MBGC, see figure) that exhibits highly desirable plasticity and superior in vitro bioactivity is described. The calcium-deficient hydroxyapatite nanocrystals that form during cement setting act as linkers between mesoporous bioactive glass particles to make the cement mechanically robust. The MGBC is promising for applications in clinical orthopedics, drug delivery, and tissue engineering.

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