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Keywords:

  • Arrays;
  • Biosensors;
  • Fluorescence;
  • Proteins;
  • Zinc oxide
Thumbnail image of graphical abstract

Enhanced fluorescence emission is detected from interacting protein pairs of dichlorotriazinylaminofluorescein-streptavidin and biotinylated bovine serum albumin (see figure) that are adsorbed onto periodically spaced, square-patterned ZnO nanostructures. This florescence-enhancement capability of nanoscale ZnO and its potential easy integration into biosensor arrays may allow ultrasensitive protein detection, which is needed in the areas of biomedical research and in large-scale testing and screening.