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Advanced Materials

Dissolving Behavior and Stability of ZnO Wires in Biofluids: A Study on Biodegradability and Biocompatibility of ZnO Nanostructures

Authors

  • J. Zhou,

    1. School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0245, USA
    2. School of Physics and Engineering, State Key Lab of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Materials and Technologies, Sun Yat-Sen (Zhongshan) University, Guangzhou 510275 (P.R. China)
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  • N. S. Xu,

    1. School of Physics and Engineering, State Key Lab of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Materials and Technologies, Sun Yat-Sen (Zhongshan) University, Guangzhou 510275 (P.R. China)
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  • Z. L. Wang

    1. School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0245, USA
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  • Z. L. Wang thanks the support from NSF, the NASA Vehicle Systems Program and Department of Defense Research and Engineering (DDR&E), and the Defense Advanced Research Projects Agency (Award No. N66001-04-1-8903). N. S. X. thanks the support of the project from the NSF of China (Grant No. 50 021 202, 50 329 201, and 90 201 020), Ministry of Science and Technology of China (Grant No. 2003CB314700 and 2002AA313010), Ministry of Education of China, Science and Technology Department of Guangdong Province, Education Department of Guangdong Province, and Science and Technology Department of Guangzhou City. J. Zhou thanks the KAISI FUND from SunYat-Sen (Zhongshan) University. We thank the help of Y. Ding, Rusen Yang, Jin Liu, Wenjie Mai, Y. Y. Zhang, and Gang Bao. Supporting Information is available online from Wiley InterScience or from the author.

Abstract

The biodegradability and biocompatibility of ZnO wires in biofluid has been studied by investigating the interaction of the wires with deionized water, ammonia, NaOH solution, and horse blood serum. The results show that ZnO can be dissolved into mineral ions by these liquids within a few hours (see figure) and that ZnO is a bio-safe, nontoxic material for in vivo biosensing and biodetection.

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