This material is based upon work supported by the U.S. Army Research Laboratory and the U.S. Army Research Office under grant number DAAD19-03-1-0227, and by the National Science Foundation through a Nanoscale Science and Engineering Center grant (DMR-0117792). We thank the anonymous reviewer for suggesting an important experiment described in this paper.
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Communication
Smart Nanomaterials Responsive to Multiple Chemical Stimuli with Controllable Cooperativity†
Article first published online: 27 JUN 2006
DOI: 10.1002/adma.200600525
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Liu, J. and Lu, Y. (2006), Smart Nanomaterials Responsive to Multiple Chemical Stimuli with Controllable Cooperativity. Adv. Mater., 18: 1667–1671. doi: 10.1002/adma.200600525
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Publication History
- Issue published online: 27 JUN 2006
- Article first published online: 27 JUN 2006
- Manuscript Accepted: 19 APR 2006
- Manuscript Received: 13 MAR 2006
- Abstract
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Keywords:
- Biosensors;
- DNA;
- Gold;
- Molecular recognition;
- Nanoparticles, metal;
- Sensors, chemical;
- Stimuli-responsive materials
Aptamer-linked smart materials responsive to a combination of any two analytes, including adenosine, cocaine, and K+, are demonstrated. The effect of small molecules on the properties of the nanomaterials can be either highly cooperative or non-cooperative, which can be described as logic gates with chemical inputs and colorimetric output (see figure).