Carbon Nanotube Monolayer Patterns for Directed Growth of Mesenchymal Stem Cells

Authors


  • Sung Y. Park, Sun Y. Park, and S. Namgung contributed equally to this work. The work in this paper was supported by the KOSEF under the National Research Laboratory (NRL) grant and by the MOCIE. S.H. acknowledges equipment support from the Nano-Systems Institute National Core Research Center program. J.-M.N. would like to thank the Korea Research Foundation Grant funded by the Korean Government (MOEHRD, Basic Research Promotion Fund; KRF-2006-C00217) and the New Faculty Supporting Grant funded by Seoul National University for their financial support. Y.P. acknowledges financial support from Seoul R&BD Program. Supporting Information is available online at Wiley InterScience or from the author.

Abstract

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Carbon nanotube (CNT) monolayer patterns are utilized to control the growth of mesenchymal stem cells (MSCs) (see figure). MSCs exhibit preferential growth on CNT patterns, suggesting that the CNT monolayer does not have a harmful effect on the MSCs. Furthermore, the growth of MSCs on swCNT patterns between electrodes is demonstrated. These results show that CNT patterns have enormous potential as a new platform for basic research and applications using stem cells.

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