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Keywords:

  • Biomedical applications;
  • Chiral separation;
  • Molecular recognition;
  • Sensors;
  • Silica
Thumbnail image of graphical abstract

Silica-based hybrid molecularly imprinted polymer (MIP) monoliths with good chiral recognition ability are synthesized (see figure) using a novel method, a room temperature ionic liquid (RTIL)-mediated, non-hydrolytic sol–gel technique. The approach avoids the cracking and shrinking of the bed during drying, which is commonly associated with conventional sol–gel processing, overcomes the shortcomings associated with conventional organic-polymer-based MIP matrices, and offers improved selectivity.