Communication

Combining Fluorescent Probes and Biofunctional Magnetic Nanoparticles for Rapid Detection of Bacteria in Human Blood†

  1. J. Gao1,
  2. L. Li1,
  3. P.-L. Ho3,
  4. G. C. Mak3,
  5. H. Gu1,
  6. B. Xu1,2

Article first published online: 10 NOV 2006

DOI: 10.1002/adma.200601058

Issue

Advanced Materials

Advanced Materials

Volume 18, Issue 23, pages 3145–3148, December, 2006

Additional Information

How to Cite

Gao, J., Li, L., Ho, P.-L., Mak, G. C., Gu, H. and Xu, B. (2006), Combining Fluorescent Probes and Biofunctional Magnetic Nanoparticles for Rapid Detection of Bacteria in Human Blood. Adv. Mater., 18: 3145–3148. doi: 10.1002/adma.200601058

Author Information

  1. 1

    Department of Chemistry, The Hong Kong University of Science & Technology, Clear Water Bay, Hong Kong, P.R. China

  2. 2

    Bioengineering program, The Hong Kong University of Science & Technology, Clear Water Bay, Hong Kong, P.R. China

  3. 3

    Center of Infection and Department of Microbiology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China

  1. †

    This work was partially supported by RGC (Hong Kong), HIA (HKUST) and a Grant from the University Department Fund Project-Research Centre of Emerging Infectious Diseases of the University of Hong Kong.

Publication History

  1. Issue published online: 27 NOV 2006
  2. Article first published online: 10 NOV 2006
  3. Manuscript Revised: 26 JUL 2006
  4. Manuscript Received: 15 MAY 2006

Funded by

  • RGC (Hong Kong), HIA (HKUST)
  • University Department Fund Project-Research Centre of Emerging Infectious Diseases of the University of Hong Kong

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (409K)

Keywords:

  • Bacteria;
  • Biomedical applications, magnetic;
  • Biosensors;
  • Fluorescence imaging;
  • Nanoparticles, magnetic
Thumbnail image of graphical abstract

Detection of bacteria in human blood within two hours is achieved through the use of vancomycin-functionalized FePt nanoparticles in combination with a vancomycin-conjugated fluorescent probe, as shown in the figure (B: bacteria; Van: vancomycin; FLA: fluorescein amine). This promises to be a sensitive and rapid protocol for detecting bacteria in blood products or other targets in biological samples.

Get PDF (409K)