Tubular Nanostructures from Degradable Core–Shell Cylinder Microstructures in Chiral Diblock Copolymers


  • We thank Prof. Benjamin S. Hsiao of the Chemistry Department, State University of New York at Stony Brook, and Dr. Igors Sics and Dr. Carlos-Alberto Avila-Orta of the National Synchrotron Light Source at Brookhaven National Laboratory for their help with synchrotron SAXS experiments. We also appreciate Ms. Pei-Chi Chao of the Regional Instruments Center at NCHU for her help with TEM experiments. Supporting Information is available online from Wiley InterScience or from the author.


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A core–shell cylinder phase is obtained from the self assembly of chiral diblock copolymers, polystyrene-b-poly(L-lactide) (PS–PLLA) with PLLA-rich fractions. After the self-assembly of the polymer chains, scrolling of the helical microdomains results in core–shell cylinder microstructures (see figure). The microstructures are then hydrolyzed to give polymeric nanotubes with potential applications in drug delivery and as nanoreactors.