Field-Driven Biofunctionalization of Polymer Fiber Surfaces during Electrospinning


  • This work was supported by the U.S. Department of Commerce through the National Textiles Center. We are immensely grateful to Dr. Markus Antonietti (Max-Planck Institute of Colloids & Interfaces) for insightful comments and Dr. Mark D. Walters (Duke University) for technical assistance with XPS measurements. H. G. B. would also like to thank the Deutsche Forschungsgemeinschaft (Emmy Noether BO1762/2) and the Max Planck Society for additional support.


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Surface-biofunctionalized synthetic polymer fibers composed of a fiber-forming host polymer and an oligopeptide conjugate are prepared by electrospinning. The conjugate consists of a polypeptide segment and a polymer block that is compatible with the host polymer. Because the more polarizable peptide segment migrates to the surface during electrospinning, peptide surface enrichment (see figure and inside cover) is achieved in a single step without further treatment.