A.S. would like to thank his co-workers from Nanomix Inc. cited in this article for their contribution to the research.
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Review
Carbon Nanotube Field-Effect-Transistor-Based Biosensors†
Article first published online: 30 APR 2007
DOI: 10.1002/adma.200602043
Copyright © 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Allen, B. L., Kichambare, P. D. and Star, A. (2007), Carbon Nanotube Field-Effect-Transistor-Based Biosensors. Adv. Mater., 19: 1439–1451. doi: 10.1002/adma.200602043
- †
Publication History
- Issue published online: 25 MAY 2007
- Article first published online: 30 APR 2007
- Manuscript Revised: 17 NOV 2006
- Manuscript Received: 8 SEP 2006
- Abstract
- References
- Cited By
Keywords:
- Biosensors;
- Carbon nanotubes;
- DNA;
- Enzymes;
- Field-effect transistors;
- Proteins
Abstract
There is an explosive interest in 1D nanostructured materials for biological sensors. Among these nanometer-scale materials, single-walled carbon nanotubes (SWNTs) offer the advantages of possible biocompatibility, size compatibility, and sensitivity towards minute electrical perturbations. In particular, because of these inherent qualities, changes in SWNT conductivity have been explored in order to study the interaction of biomolecules with SWNTs. This Review discusses these interactions, with a focus on carbon nanotube field-effect transistors (NTFETs). Recent examples of applications of NTFET devices for detection of proteins, antibody–antigen assays, DNA hybridization, and enzymatic reactions involving glucose are summarized. Examples of complementary techniques, such as microscopy and spectroscopy, are covered as well.