Advanced Materials

A Multiprotein Microarray on Silicon Dioxide Fabricated by Using Electric-Droplet Lithography


  • This work was supported by a grant from the Interdisciplinary Research Collaboration (IRC) in Nanotechnology (E.M.B., P.M.). S.A.N. was supported by a Wellcome Trust programme grant to M.A.H.


Sequential electric droplet lithography (EDL) was demonstrated on silicon dioxide to create a functional multiprotein array with minimum cross contamination. Each EDL cycle consists of charge writing on a dielectric substrate and subsequent electrostatic attachment of microdroplets containing the protein of interest to the charge pattern (see figure).

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