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Keywords:

  • Biocompatible materials;
  • Catalysts;
  • Nanotubes, single-walled;
  • Nickel
Thumbnail image of graphical abstract

The biomolecular mechanism of nickel carcinogenicity is driven by intracellular Ni cation. The role of nickel catalyst in single-wall carbon nanotube toxicity will therefore depend on its bioavailability, which is highly uncertain due to encapsulation by carbon shells. This article measures the material-specific Ni release into extra- and intracellular physiological fluid phases and suggests practical techniques for managing the metals contribution to SWNT toxicity.