Drosophila as a Live Substrate for Solid-State Microfabrication


  • The authors acknowledge the National Science Foundation (Award #0533100) and the ARCS Foundation (WRF Fellowship) for financial support; the authors also thank John Lund for his time and expertise in preparing the images.


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Drosophila shows a surprisingly high resilience to vacuum exposure. A systematic study shows that some flies survive even after three hours of residence in a few mTorr vacuum. This observation opens the way for using Drosophila as a substrate for direct solid-state microfabrication and incorporation of inorganic microstructures for hybrid biological/abiological manufacturing and microrobotics applications.