The authors thank the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie for financial support. We are grateful to Dr. Klaus Pelz for providing the S. aureus cells and to Julia M. Weiss for bacterial testing.
Design of Contact-Active Antimicrobial Acrylate-Based Materials Using Biocidal Macromers†
Article first published online: 2 JAN 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 20, Issue 1, pages 104–108, January, 2008
How to Cite
Waschinski, C. J., Zimmermann, J., Salz, U., Hutzler, R., Sadowski, G. and Tiller, J. C. (2008), Design of Contact-Active Antimicrobial Acrylate-Based Materials Using Biocidal Macromers. Adv. Mater., 20: 104–108. doi: 10.1002/adma.200701095
- Issue published online: 2 JAN 2008
- Article first published online: 2 JAN 2008
- Manuscript Revised: 5 SEP 2007
- Manuscript Received: 7 MAY 2007
- Deutsche Forschungsgemeinschaft
- Fonds der Chemischen Industrie
- Antimicrobial materials;
- Network structures
A self organizing antimicrobial finish on acrylate-based materials was achieved by adding only 0.4 wt% of a biocidal macromer to the monomer mixture prior polymerization. The materials surface kills the infectious bacterium Staphylococcus aureus without releasing the biocide (Figure, lower section) and stays active even after 45 d of constant washing. Confocal Raman spectroscopy and fluorescence microscopy (Figure, upper section) reveal that the biocide has migrated to the surface of the materials during polymerization.