Advanced Materials

Structural Phase Coexistence under Reversible Thermal Control

Authors

  • C.-M. Cheng,

    1. Departments of Mechanical and Biomedical Engineering, and Biological Sciences, Carnegie Mellon University, Scaife Hall, 5000 Forbes Avenue, Pittsburgh, PA 15213 (USA)
    Search for more papers by this author
  • P. R. LeDuc

    1. Departments of Mechanical and Biomedical Engineering, and Biological Sciences, Carnegie Mellon University, Scaife Hall, 5000 Forbes Avenue, Pittsburgh, PA 15213 (USA)
    Search for more papers by this author

  • This work was supported in part by the National Science Foundation-CAREER, National Academies Keck Foundation Futures Initiative, Pennsylvania Infrastructure Technology Alliance, the Department of Energy-Genome to Life, and the Beckman Young Investigators Program (P.R.L.). C.-M. C. was supported in part by a PhD Research Scholarship from Taiwan and the Dowd-ICES Scholarship from Carnegie Mellon University, USA

Abstract

Phase transition and coexistence are observed to define behaviors and enable advances in a variety of areas. We show that alterations in the cell structure for actin cytoskeleton produces distinct phases based on changes in the thermal environment. These studies suggest that the entire cell as well as subcellular regions may have distinct phases or patterns that retain a reversible equilibrium directly related to the thermal environment.

original image

Ancillary