This work was supported by the American Cancer Society under grant number IRG-77-004-28.
Self-Assembly of Cell–Microparticle Hybrids†
Article first published online: 12 FEB 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 20, Issue 5, pages 989–993, March, 2008
How to Cite
Krishnamachari, Y., Pearce, M. E. and Salem, A. K. (2008), Self-Assembly of Cell–Microparticle Hybrids. Adv. Mater., 20: 989–993. doi: 10.1002/adma.200701689
- Issue published online: 28 FEB 2008
- Article first published online: 12 FEB 2008
- Manuscript Revised: 31 JUL 2007
- Manuscript Received: 11 JUL 2007
- American Cancer Society. Grant Number: IRG-77-004-28
- Hybrid materials;
Synthetic-biological hybrids of biodegradable microparticles and transfected cells are assembled, as schematically illustrated in the figure. The cells are surface-functionalized with biotin and the particle surface is also engineered with biotin. Avidin is then used as a bridging protein to bind together the microparticles and the surface- functionalized cells.