Designed Fabrication of a Multifunctional Polymer Nanomedical Platform for Simultaneous Cancer- Targeted Imaging and Magnetically Guided Drug Delivery


  • T.H. thanks the Korean Ministry of Science and Technology for financial support through the National Creative Research Initiative Program of the Korea Science and Engineering Foundation (KOSEF). T.G.P. is supported by the National Research Laboratory Grant from the Ministry of Science and Technology. J.H.L. is supported by the Center for Biological Modulators of the 21st Century Frontier R&D Program. Supporting Information is available online from Wiley InterScience or from the authors.


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Multifunctional polymer nanomedical platforms make simultaneous cancer-targeted MRI or optical imaging together with efficient drug delivery in vitro possible. In addition, clusters of Fe3O4 nanoparticles loaded in the polymer nanoparticles endow the magnetic guiding of the polymer particles, providing synergetic targeting efficiency.