Electrically Programmable Surfaces for Configurable Patterning of Cells


  • The authors thank Y.-W. Lin for assistance with electrode lithography. This work was supported by NSF, Yamatake Co., Japan, NIH, and an REA Fellowship from the University of Michigan (C.Y.F.).


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A microfluidic device surface coated with block copolymer and extracellular matrix (ECM) protein layers (see Figure) shows electrical programmability for cell immobilization. The surface has demonstrated the ability to pattern C2C12 murine myoblasts cells with their morphology and surface density adjustable by varying the applied electrode bias.