Communication

Sensitivity Enhancement of Surface-Plasmon Resonance Imaging by Nanoarrayed Organothiols†

  1. Patrícia Lisboa,
  2. Andrea Valsesia,
  3. Ilaria Mannelli,
  4. Stephane Mornet,
  5. Pascal Colpo*,
  6. François Rossi

Article first published online: 15 MAY 2008

DOI: 10.1002/adma.200702736

Issue

Advanced Materials

Advanced Materials

Volume 20, Issue 12, pages 2352–2358, June 18, 2008

Additional Information

How to Cite

Lisboa, P., Valsesia, A., Mannelli, I., Mornet, S., Colpo, P. and Rossi, F. (2008), Sensitivity Enhancement of Surface-Plasmon Resonance Imaging by Nanoarrayed Organothiols. Advanced Materials, 20: 2352–2358. doi: 10.1002/adma.200702736

Author Information

  1. European Commission, Institute of Health and Consumer Protection, NMI TP203, Via E. Fermi 2749, 21021 Ispra (VA) (Italy)

*European Commission, Institute of Health and Consumer Protection, NMI TP203, Via E. Fermi 2749, 21021 Ispra (VA) (Italy).

  1. †

    We thank Simone Malfara and Giovanni Maselli for technical support.

Publication History

  1. Issue published online: 18 JUN 2008
  2. Article first published online: 15 MAY 2008
  3. Manuscript Revised: 10 FEB 2008
  4. Manuscript Received: 5 NOV 2007

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (313K)

Keywords:

  • biomolecules;
  • colloidal lithography;
  • detection;
  • immunosensors;
  • nanopatterning;
  • nanoarrays;
  • organothiols;
  • surface-plasmon resonance imaging

Graphical Abstract

Thumbnail image of graphical abstract

Crystalline organothiol nanoarrays improve the detection sensitivity of surface-plasmon resonance (SPR) by a factor of five in comparison to noncrystalline nanopatterns and uniformly carboxylic surfaces. SPR images taken during the detection of an immunoreaction show a brighter color in the nanoarray area of the surface, which is the result of higher detection sensitivity. Sensor surfaces with nanoarrays may therefore provide future applications for the immobilization of biomolecules on biosensing surfaces.

Get PDF (313K)