Communication

Protein In-Mold Patterning†

  1. Susan B. N. Biancardo1,
  2. Henrik J. Pranov2,
  3. Niels B. Larsen1,*

Article first published online: 17 APR 2008

DOI: 10.1002/adma.200702859

Issue

Advanced Materials

Advanced Materials

Volume 20, Issue 10, pages 1825–1829, May 19, 2008

Additional Information

How to Cite

Biancardo, S. B. N., Pranov, H. J. and Larsen, N. B. (2008), Protein In-Mold Patterning. Advanced Materials, 20: 1825–1829. doi: 10.1002/adma.200702859

Author Information

  1. 1

    Department of Micro- and Nanotechnology Technical University of Denmark DTU Nanotech, Frederiksborgvej 399, 4000 Roskilde (Denmark)

  2. 2

    Department of Manufacturing Engineering and Management Technical University of Denmark 2800 Kgs. Lyngby (Denmark)

*Department of Micro- and Nanotechnology Technical University of Denmark DTU Nanotech, Frederiksborgvej 399, 4000 Roskilde (Denmark).

  1. †

    The authors thank Nikolaj Gadegaard for facilitating the writing of master structures. We are indebted to Nikolaj Gadegaard, Henrik K. Rasmussen, Keld West, and Rolf H. Berg for fruitful discussions. This work was supported by the Danish Ministry for Science, Technology and Innovation, (“Centre for Nanostructured Polymer Surfaces for Medical Applications”, grant 2002-603-4001-87 and FTP grant 9901663), and the Technical University of Denmark.

Publication History

  1. Issue published online: 23 MAY 2008
  2. Article first published online: 17 APR 2008
  3. Manuscript Revised: 8 FEB 2008
  4. Manuscript Received: 18 NOV 2007

Funded by

  • Danish Ministry for Science, Technology and Innovation
  • “Centre for Nanostructured Polymer Surfaces for Medical Applications”. Grant Numbers: 2002-603-4001-87, 9901663

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Keywords:

  • biocompatible materials;
  • patterning;
  • proteins;
  • injection molding;
  • microcontact printing

Graphical Abstract

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Nano-and microscopic patterns of active proteins may be built into the surface of polymers during injection molding of hot polymer melts. The retained biofunction is likely due to extremely fast (nanoseconds) cooling rates within nanometers of the cold mold/hot melt interface.

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