Get access
Advanced Materials

Protein In-Mold Patterning

Authors

  • Susan B. N. Biancardo,

    1. Department of Micro- and Nanotechnology Technical University of Denmark DTU Nanotech, Frederiksborgvej 399, 4000 Roskilde (Denmark)
    Search for more papers by this author
  • Henrik J. Pranov,

    1. Department of Manufacturing Engineering and Management Technical University of Denmark 2800 Kgs. Lyngby (Denmark)
    Search for more papers by this author
  • Niels B. Larsen

    Corresponding author
    1. Department of Micro- and Nanotechnology Technical University of Denmark DTU Nanotech, Frederiksborgvej 399, 4000 Roskilde (Denmark)
    • Department of Micro- and Nanotechnology Technical University of Denmark DTU Nanotech, Frederiksborgvej 399, 4000 Roskilde (Denmark).
    Search for more papers by this author

  • The authors thank Nikolaj Gadegaard for facilitating the writing of master structures. We are indebted to Nikolaj Gadegaard, Henrik K. Rasmussen, Keld West, and Rolf H. Berg for fruitful discussions. This work was supported by the Danish Ministry for Science, Technology and Innovation, (“Centre for Nanostructured Polymer Surfaces for Medical Applications”, grant 2002-603-4001-87 and FTP grant 9901663), and the Technical University of Denmark.

Abstract

Nano-and microscopic patterns of active proteins may be built into the surface of polymers during injection molding of hot polymer melts. The retained biofunction is likely due to extremely fast (nanoseconds) cooling rates within nanometers of the cold mold/hot melt interface.

original image
Get access to the full text of this article

Ancillary